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Preisträger Prof. Dr. Michael J. Berridge

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Name: Sir Michael John Berridge
Date of Birth: October 22, 1938
Place of Birth: Gatooma, Rhodesia
Address: The Babraham Institute, Laboratory of Molecular Signalling, Babraham Hall, Babraham, Cambridge CB2 4AT, UK

1960 BSc, University College of Rhodesia and Nyasaland, Salisbury, Rhodesia, 1st Class honors
1965 PhD, University of Cambridge (Supervisor: Sir Vincent B. Wigglesworth)

Vocational Experience
1965-1966 Post-doctoral Fellow, University of Virginia (with Prof. D. Bodenstein)
1966-1967 Post-doctoral Fellow, Case Western Reserve University (with Dr. M. Locke)
1967-1969 Research Associate, Case Western Reserve University (with Dr. B. Schmidt-Nielsen)
1969-1972 Senior Scientific Officer, Unit of Invertebrate Chemistry and Physiology (Director Dr. J. E. Treherne), Cambridge University
1972-1978 Principal Scientific Officer, Unit of Invertebrate Chemistry and Physiology, Cambridge
1978-1990 Senior Principal Scientific Officer, Unit of Insect Neurophysiology and Pharmacology, Cambridge
since 1990 Deputy Chief Scientific Officer (Grade 4), Laboratory of Molecular Signalling, Babraham Institute
1972-1986 Elected Title C Fellow, Trinity College, Cambridge
since 1986 Elected Title B Fellow, Trinity College, Cambridge
1984 Elected Fellow of the Royal Society
since 1994 Honorary Professor of Cell Signalling, University of Cambridge
1988 Honorary Fellowship - Gonville and Caius

Awards and Grants
1984 Feldberg Prize
1986 The King Faisal International Prize in Science
- Louis Jeantet Prize in Medicine
1987 William Bate Hardy Prize, Cambridge Philosophical Society
- Abraham White Scientific Achievement Award, The George Washington University School of Medicine
1988 Gairdner Foundation International Award
1989 Albert Lasker Basic Medical Research Award
- Baly Medal, Royal College of Physicians, London
1990 Rita Levi Montalcini Award Lecture, Fidia Research Foundation, Washington, DC
- Dale Medal, Society for Endocrinology
1991 CIBA-GEIGY/DREW Award in Biomedical Research
- Royal Medal, The Royal Society
1993 Degree of Doctor Honoris Causa, Limburgs Universitair Centrum, Belgium
1994 Dr. H. P. Heineken Prize for Biochemistry and Biophysics
1995 The Wolf Foundation Prize in Medicine, Israel
1996 The Massry Prize in Nephrology, Physiology and Related Fields, The Meira and Shaul G. Massry Foundation, USA
1998 Knight Bachelor
1999 Ernst Schering Prize, Ernst Schering Research Foundation, Berlin

Membership of Societies
- Honorary Member, Japanese Biochemical Society
- Society of General Physiologists
1989 Academia Europaea
1991 European Molecular Biology Organization (EMBO)
1992 Honorary Member, American Physiological Society
1994 Foreign Correspondent, Académie Royale de Médecine de Belgique
1995 Honorary Life Member, Society for Experimental Biology
1998 The Academy of Medical Sciences, London
1999 Foreign Associate of the National Academy of Science, Washington, DC

Editorial Work
1971-1985 Co-editor (with Sir Vincent Wigglesworth and Dr. J. E. Treherne), Advances in Insect Physiology
1980-1981 Editorial Board, Cell Calcium
1981-1984 Editorial Advisory Panel, Molecular and Cellular Endocrinology
1987 Editorial Advisory Board, Journal of Neuroendocrinology
1989 Editorial Board, Molecular Biology of the Cell (formerly Cell regulation)
1989-1992 Advisory Editorial Board, Cancer Cells
1990 International Advisory Board, Advances in Second Messenger and Phosphoprotein Research
1990 Editorial Board, Journal of Basic and Clinical Physiology and Pharmacology
1993 Editorial Board, Journal of Experimental Biology
1994 Advisory Editor to Bio Essays
1994-1996 Editorial Board, Japan Society for Cell Biology's official journal, Cell Structure and Function

Major Research Interest
The main area of research interest concerns the mode of action of hormones and neurotransmitters at the cellular level. The problem is to understand how cells detect external signals and translate them into the intracellular signals (cyclic nucleotides and calcium) responsible for triggering a change in cellular acitivity.
Current interest centers around the role of inositol lipids in the action of calcium-mobilizing hormones. Studies are concentrated on the way in which agonists act to stimulate the hydrolysis of these lipids to release both diacylglycerol and inositol trisphosphate (IP3). Attention is being focused on the role of IP3 in controlling the spatiotemporal aspects of calcium signalling with particular emphasis on the neural processes of membrane excitability, learning and memory.

Award Lectures
1984 Annual Bayer AG Lecture in Pharmacology, Yale University School of Medicine
1985 Halliburton Lecture, Kings College, London
- Harrison Lecture, Endocrine Society of Australia
1986 Nelson Medical Lecture, University of California, Davis
1987 Welcome Visiting Professor, The University of Texas Medical School
- The N I H Lecture
- ICI Prize Lecture, University of Manchester
- The Baule Distinguished Lecture in Neurosciences, Syracuse
- The Alice and Joseph Brooks International Lecture in Neurosciences, Harvard Medical School
1988 16th FEBS Ferdinand Springer Lecture
- Royal Society Croonian Lecture
- 18th Annual Schueler Distinguished Lecture in Pharmacology, Tulane University
- Smith Kline and French Lecture, University of London
- 2nd Hillarp Lecture, European Neurosciences Association, Zurich
- Ralph Dorman Lecture, Stanford University School of Medicine
- Steinhouse Memorial Lecture, University of California, Irvine
- Robert E. Olsen Lecture, St. Louis University School of Medicine
- Hillarp Memorial Lecture, Bioscience 88, Malmo, Sweden
1989 Harold Lamport Lecture, University of Washington, Seattle
- Flexner Lecture, Vanderbilt University, Nashville
- Chilton Lecture, University of Texas, Dallas
- Boxer Lecture, University of Medicine and Dentistry of New Jersey
- Samuel Rudin Visiting Professorship, Columbia University
1990 Dame Honor B. Fell Lecture, Cardiff
- Charnock Bradley Memorial Lecture, University of Edinburgh
- John R. Murlin Lecture, University of Rochester
- College of Medicine Distinguished Lecturer, University of Iowa
- Leslie L. Bennett Lecture, University of California, San Francisco
- The Inaugural Albert L. Lehninger Lecture, The Johns Hopkins University, Baltimore
- Frank Rose Memorial Lecture, British Association for Cancer Research
- Falk Memorial Lecture, NIEHS, Research Triangle Park
- The ICI Guest Lecture, Medical Research Society, UK
1992 The 19th Annual Calbiochem Lectureship in Chemistry, University of California, San Diego
- The Poulsson Lecture, University of Oslo
1993 The Donald W. Seldin Lecture, The 12th International Congress of Nephrology, Jerusalem
1994 The 14th Dr. Abraham White Memorial Lecture, Syntex, Palo Alto, California
- Storer Life Sciences Lecture, University of California, Davis
1995 Bidder Lecture, The Society for Experimental Biology
- Hugh Davson Distinguished Lectureship, The American Physiological Society
1996 Applebaum Distinguished Lecturer, The University of Florida, Gainesville
- Annual Review Prize Lecture, The Physiological Society
- Dr. Aaron I. Grollman Visiting Lectureship in Basic Medical Sciences, University of Maryland, Baltimore
1997 6th Choh Hao Li Memorial Lecturer, University of California, Berkeley
1999 Edwin G. Krebs Lecture in Molecular Pharmacology, University of Washington School of Medicine, Seattle
- First Fred Fay Lecture, University of Massachusetts Medical School, Department of Physiology


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