Philipp Lachenmann: DELPHI Rationale


Ernst Schering Prize 2012

Prof. Dr. Matthias Mann

On the 10th of September 2012 the Schering Foundation Berlin will award the Ernst Schering Prize 2012 for internationally leading accomplishments in the area of medical, biological and chemical basic research to Prof. Matthias Mann, director at the Max-Planck-Institute of Biochemistry in Martinsried. He will receive the prize, which carries an award of 50,000 Euro, for his seminal work exploring the proteome – the complete complement of the proteins of an organism. Matthias Mann has revolutionized the methods that are used for the identification and characterization of proteins, by successfully transferring methods of the physical sciences – such as mass spectrometry – to the area of molecular biology.

Not genes but protein molecules, whose structures are laid down in the genetic material, are the real carriers of function in the cell. The analysis of proteins of organisms is therefore one of the most important tasks in biology and medicine. Matthias Mann’s research is making it possible to analyze the proteome with the same efficiency that was previously reserved for the genome (the total genetic material of an organism). Applying and continuously refining methods of the physical sciences such as electrospray ionization and mass spectrometry to the analysis of biological systems, now enables comprehensive cataloging of proteins and their interconnections. The bioinformatic software algorithms that Matthias Mann has developed over the years are an important prerequisite for these developments. These developments are crucial foundations of proteomics, a new scientific field whose aim is the identification and quantification of proteins in an organism and of which Matthias Mann was one of the founders. A goal of proteomics is to chart all the proteins of a cell or an organ and to thereby find hints to their function or malfunction in a disease. The application of proteomics spans from the identification of microorganisms to stem cell research and aging research and it has already lead to many novel insights and discoveries in the medical sciences. For instance, researchers can now compare healthy tissues with cancer tissues to find out which proteins are involved in cancer. Very recently, Matthias Mann has developed a method for the fast and precise determination of proteins in cancer tissues, which is now being investigated for its clinical applicability.

Matthias Mann studied physics and mathematics at Gottingen University and obtained his Ph.D. in chemical engineering at Yale University. Here he was decisively involved in the development of electrospray ionization, which has become a key technology of the life sciences. As a post-doctoral fellow and later as a professor for bioinformatics at the University of Southern Denmark in Odense, he developed amongst others techniques the first bioinformatic search algorithms for peptide fragmentation data and SILAC, a new method of quantitative proteomics and a breakthrough in the mapping of protein interactions. Since 2005 Matthias Mann is director at the Max-Planck institute of biochemistry and since 2009 also the department head of proteomics at the Novo Nordisk Foundation Center for Protein Research in Copenhagen. Besides the Ernst Schering Prize, he will receive the Gottfried Wilhelm Leibniz Prize of the German Research Foundation in 2012, which entails a 2.5 million Euro research grant.

Important dates

Press conference with the Prize Winner
September 10, 2012, 11:15 a.m.
Schering Stiftung | Unter den Linden 32-34 | 10117 Berlin

Award Ceremony „Ernst Schering Prize 2012“
September 10, 2012, 5 p.m.
Participation by invitation only

Lectures of the Prize Winner
September 11, 2012, in the morning
Lecture for pupils in Berlin-Center (non public lecture)

September 11, 2012, 6:15 p.m.
Public Lecture for Scientist and Students

Berlin-Brandenburg Academy of Sciences and Humanities
Jägerstr. 22/23 | 10117 Berlin

The lecture will be in English.
Registration is not necessary.

Futher informationen

Andrea Bölling, Project Manager Science of the Ernst Schering Foundation:
This e-mail address is being protected from spambots. You need JavaScript enabled to view it | 030-20 62 29 60

Foto: © Max-Planck-Institute for Biochemistry


Curriculum Vitae


Hybrid Encounters. Tomás Saraceno and Guests

18.04.2018. Berlin | With Hybrid Encounters, the Hybrid Plattform and the Schering Stiftung have created an...

The Unseen Universe (An Introduction to Particle Physics)

26.04.2018, Berlin | For his video work DELPHI Rationale, the artist Philipp Lachenmann filmed at the...

Live-Debatte: Arm durch Wohnen? Wie Mieten bezahlbar bleiben

16.05.2018, Berlin/Braunschweig | Die Mieten in Deutschland steigen kontinuierlich: Seit 2010 zahlen Bundesbürger im Durchschnitt 30...