Philipp Lachenmann: DELPHI Rationale


Unlocking the Mysteries of Gastric Cancer – Studying Gastric Organoids

02.05.2018, Berlin | Gastric cancer is the third leading cause of cancer deaths. A large part of these cases can be attributed to infections with one of two pathogens: Helicobacter pylori and the Epstein-Barr virus. It is currently unclear how these two pathogens cause cancer and why some patients develop cancer while others stay healthy. Using gastric organoids from patient tissue, the lab of Dr. Sina Bartfeld at the Research Center for Infectious Diseases at the University of Würzburg studies the effect of the pathogens on the gastric cells to better identify risk factors and develop new therapies against stomach cancer. Dr. Bartfeld will talk about her research at the Integrative Research Institute (IRI) for the Life Sciences at HU Berlin on May 3, 2018, at 4 p.m. Her lecture, titled “Infection, inflammation and cancer in the GI tract – stem cell-derived organoids as model,” kicks off the IRI-Schering Colloquium on “Organoids – Life in 3D,” which is offered by the IRI Life Sciences in the summer term.

Sina Bartfeld

IRI-Schering Colloquium on “Organoids – Life in 3D”

Organoids are much simplified miniature versions of real organs grown in vitro. They consist of different, organ-specific cell types that form a functional unit and partly reproduce the functions of a real organ. The manifold application potential of organoids lies in modeling diseases and drug tests to develop therapies. In future, organoids could replace animal models.

In the 2018 summer term, the Integrative Research Institute for the Life Sciences at HU Berlin offers a colloquium entitled “Organoids – Life in 3D.” The colloquium consists of five lectures by international scientists who will present different research approaches and application areas of organoids in infection, cancer, and brain research. In addition to participating in the discussions following the lectures, young scientists will have the opportunity to discuss their research and get inspired during one-on-one meetings with the scientists. The Schering Stiftung supports the colloquium, since it addresses important aspects of life science basic research and encourages the cross-disciplinary networking of Berlin-based scientists.

The IRI-Schering Colloquium is aimed at students, PhD candidates, and researchers. The public is welcome. The lectures will be in English. Registration is not required.

Integrated Research Institute for the Life Sciences
Michaelis Bldg. 18 | Maud Menten Hall (3rd floor)
Philippstr. 13 | 10115 Berlin

pdf Program for Download

May 3, 2018
Sina Bartfeld (University of Würzburg)
Infection, inflammation and cancer in the GI tract – stem cell-derived organoids as model

June 7, 2018
Thi-Phuong Tao (TissUse GmbH Berlin)
Multi-organ-chip technology: a novel approach to predictive substance testing

July 5, 2018
Marc Leushacke (A*Star IMB Singapore)

September 6, 2018
Jarno Drost (Princess Máxima Center Utrecht)
Organoids in cancer research

October 11, 2018
Joshua Bagley (IMBA Vienna)
Using brain organoids to study human interneuron migration



Founded in 2002 by Schering AG, Berlin, the independent and non-profit Ernst Schering Foundation aims to promote science and art ...